Sunday, January 23, 2011

Simultaneous chest stroma Sarcoma and breast carcinoma: a case report

Breast cancer is one of the main health problems in the world and affects a large number of women across the globe. This group of neoplasms rarely presented as bilateral disease and, if it happens usually occurs within the we report same histological type a rare case of concurrent bilateral breast cancer with two different types of histology, a carcinoma of the breast and a chest Sarcoma in a 42-year-old woman in accordance with our hospital.

A 42-year-old Caucasian woman admitted to our Institute in August 1999, presented with a node in the left breast 3.0 x 2.5 cm and in the right breast one 1.0 cm suspected the viciousness and clinically negative with a armpit. Invasive mammary Carcinoma (right chest) and Sarcoma (left chest) had uncovered biopsies. Was presented to bilateral modified radical mastectomy. A histological study showed an invasive mammary carcinoma degree lobular Pleomorphic type II invasion of seven of the 19 excised axillary node right chest and the left chest, a sarcoma of the MOM stroma for Immunohistochemistry study for epithelial biomarker negative and positive for Vimentin. Later wall and axillary node on the left was presented you for chemotherapy (six cycles of 75 mg / m2 5-fluorouracil, epirubicin and cyclophosphamide) followed by radiotherapy of the thoracic. Hormone receptors were positive in the right breast tumor and tamoxifen 20 mg was followed by Letrozole, 2.5 mg, daily (five years) required on a daily basis (five years). She introduced the negative trend in the last consultation no characters.

The risk of developing bilateral breast cancer is about 1% every year in a similar histological type, but it is higher in tumors with lobular histology. In this case, the patient, two histologically distinct tumors proof thus presents a rare situation.


View the original article here